Dopamine anxiety reddit My self confidence has significantly increased. the benefits are amazing because it helps with oxidative stress and helps repair glutathione deficiency and a list of other benefits Exercise increases dopamine levels in the brain through a calcium-dependent process that regulates numerous brain functions. If this is the case, it could actually be really beneficial to me to do both. If you characterize the disease as this dopamine shortage, the rest pretty much makes sense. A person who is constantly searching for dopamine does not fit into society from a young age, so cue depression and anxiety nearly every time. From my personal experience, and from my clinical background, they are both quite helpful for anxiety so you shouldn’t worry about being move across to concerta. The rate limiting factor in this equation is the amount of tyrosine hydroxylase. I binge occasionally because of my anxiety, some things that have helped me: sweet or nice tea and an electric tea pot, I have 2-5 cups daily, sugar free lollipops, and jello made normally and in gummies, also popcorn with different flavors and sauces. Dopamine and other neurotransmitters cannot cross the blood-brain barrier. I also take prazosine (prescription) which prevents anxiety attacks but is non-psychoactive. This may be different for neuroatypical people with ADHD where dopamine sensitivity is high. Pubmed. The myth of 'Dopamine detoxes' and dopamine is 'bad' are social media trends not based on science. (Recent conclusion). Basically title. The result of a multi-decade marketing campaign by drug makers trying to simplify things for a TV audience, and a good-faith effort by psychiatrists trying to condense 8+ years of schooling into a two minute soundbite for consumption by their patients, has resulted in the general public accepting an explanation of dopamine, serotonin, and the rest that is self-contradictory and simply doesn There are two 'types' of dopamine: tonic and pulsatile. (I did read something about how micro dosing stimulants can lead to permanent issues with anxiety and panic attacks because it messes with your dopamine system and actually makes you more sensitive to stimulants, but I don't know if taking 2. Same! Anxiety about box condition, room to display, having to get protectors, it’s a very expensive hobby. I suspect that it may be related to serotonin’s action at the 2C and 3 receptors. He also mentions some other techniques in generating dopamine eg working on a focussed specific goal, be it physical or mental, releases dopamine. I started 10mg of Paxil for anxiety about 5 weeks ago and what it has done for me is astonishing. 1: Vitamin D can affect Dopamine levels. Also on cymbalta 40 mgs for depression and supposedly anxiety along with 10 mg of Lexapro. Good news is this is not permanent and you can increase the number of dopamine receptors to return to a normal baseline. I don't know why these self-help pseudo-science blogs call it a "dopamine detox". Well, dopamine plays a role in attention, learning, memory, and reward so yeah everybody is "addicted" to dopamine. Distress in social situations, causing impaired functioning in daily life. As for the Glycine, I take Magnesium Glycinate so I get it that way but another good mild sleepy combination I found is taking NAC with magnesium glycinate but that's just the bonus side effect. on stims is the same as their “anxiety” they probably don’t have an anxiety disorder, and are just nervous people. I have found that MMA is amazing! it's not mundane, and it trains your fight or flight response which helps with anxiety. I would strongly recommend trying those before trying SAM-e. The dopamine goes up during the activitiy, then dips after the activity. Aug 22, 2024 · As research has progressed, scientists have begun to uncover the surprising ways in which other neurotransmitters, including dopamine, contribute to anxiety symptoms and disorders. So even if depression was just "low dopamine", tyrosine wouldn't help. Any dopamine produced by tyrosine in the body, as a result of taking B6 with tyrosine, cannot make it into the brain. Personal opinion also, we are 10 years away from acknowledging that adhd is a particular subset of the spectrum. Saffron for me has been a lifesaver, in terms of reducing depression, which has made my anxiety much better. IMO There’s nothing wrong with being “medicated every day”. In my experience SAM-e feels like it tanks my dopamine, but everyone’s different. NAC also regulates glutamate levels and glutamate regulates how much dopamine, serotonine etc. I'm also on prescription meds (check for interactions!), medical cannabis, and successfully completed CBT some time ago. Too little dopamine, you don't "worry" about anything. is fired out. Too much Dopamine in the limbic system causes fear, anxiety and paranoia. It literally took me years to start taking it and it’s absolutely changed my life since starting it. Social media, tiktok, games, porn, movies, tv shows Etc. And it's not uncommon for people today to self medicate with drugs, alcohol, sex, masturbation. I know that low levels of serotonin are responsible for depression, mood, self esteem, and others. It's incredibly challenging, but I'm committed to enduring the anxiety as it is and working through practical solutions to address it. I’ve done this and it’s worked great but… I was wondering what are some other ways you can increase your dopamine naturally ? I’m really struggling to focus these days even though I’m on There are loads of relevant YouTube videos as well as Facebook forums and even a couple Reddit forums - but an easy place to start is the MeatRx website - take a peak at the success stories and look at the ones related to depression, anxiety, bi-polar, mental health (I think you can sort by key words and category). Mirtazapine at high doses is a really good antidepressant. As described in the title. You have a problem with anxiety which is a normal human emotion and your trying to fix it by taking multiple supplements that your body more than likely doesnt need, the minute you get an adverse reaction it adds to the panic and the need to search even more for answers and so you end up miles down a rabbit hole, stop wasting money and making Ever since childhood, i have experience anxiety, and depression that goes on and off. Sabroxy works best when combined with a dopamine It's a natural source of L-dopa. Ashwagandha may also help for anxiety from slow comt. g setting up little simple and achievable tasks and completing them. Also theanine (~200mg) when i'm having anxiety works very well. Journal Discussion and support for sufferers and loved ones with anxiety conditions | discord. Something about pain receptors, and the body releasing dopamine as a response, and apparently people are pretty addicted to the stuff. Get the Reddit app Scan this QR code to download the app now. Reddit thread on same topic Certain second generation antipsychotics cause Dopamine D3 receptor internalization and breakdown. If anyone did, how did you overcome them without going back to the old habbits, how would I cope with the anxiety. Any depression would be caused by imbalances of Serotonin and Dopamine uptake and re-uptake. Although I must say that if yo Supposedly gives your body the same kind of dopamine rush as sugar, just as addicting but minus the negative insulin side effects. 5>10>12. Apparently if you have low serotonin (dopamine dominance) you're constantly chasing your next "goal" and will never be satisfied because you can't ever achieve it. That is how you start feeling those weird feelings. I only found this link that describes it (listed under the significance statement section) all the references were too technical for me to understand. It is only prescribed for anxiety depression and other mood or compulsive disorders. All three types of medicines can cause a side-effect of anxiety but most people can take them without that happening. Eventually it damages the receptors. [12] Ain’t a cure, but after 35 years of living with my hair on fire… the anxiety (after meds and a huge burnout) went away, I’ve had to find gentler sources that last longer and don’t leave me so lethargic moments after the experience. A nasty cocktail of hormones that the vast majority of people love to intentionally ignore because "love is special", when in reality it's just your brain on its own drugs. It makes me give just enough of a shit about my job to actually do it. These support the metabolic pathways for serotonin and catcecholamine synthesis (dopamine, noradrenalin, etc) Hello everyone, In the episode about dopamine,Huberman says that you can raise your base line “wavepool” of dopamine by taking a cold shower. It becomes more of a task, especially having to look at several resellers to make sure you’re getting something authentic and in good condition. Good luck! This is relevant as dopamine is thought to be involved in the pathophysiology of depression, and increased dopaminergic signaling by sertraline in addition to serotonin may have additional benefits against depression. At lower doses it is good for insomnia and anxiety. (Dopamine Detox) This is by far the most important thing you can do. If the reason why you wanna boost dopamine is to get more energy to do stuff my tip is get l-theanine and add it to your coffee. As far as my layman's understanding of adhd goes, the prefrontal cortex has the dopamine disorder and stimulants compensate for this with a bit of a shotgun, haphazard approach, the massive dopamine release/reuptake inhibiton from stimulants inevitably also effects the reward centres of the brain as well which we know causes euphoria and that On the other side seeking out pleasure at all costs, not allowing yourself to get bored, etc. The relationship between dopamine and anxiety is a complex and sometimes counterintuitive one. That said, I have no idea how long I've had this, but I have ALWAYS struggled with my mental health. Tonic dopamine is the rather constant background level, whereas pulsatile are the brief spikes due to some stimulus. 5>15 (came off Wellbutrin completely here, but 15 buspirone alone wasn’t enough to quell my anxiety so went up to 20. Sabroxy doesn't make more of anything, it just increases the amount of time dopamine hangs around outside of neurons. This is an interesting article on serotonin and dopamine and how, when they're out of balance, it can cause various problems (depression, anxiety, etc). Reducing most stimulation. Regular aerobic exercise has a protective effect on D2 dopamine receptor levels, also preventing any modifications in dopamine metabolism due to the aging process. These all stimulate our brain excessively and provide way too much dopamine. It helped with the symptoms coming from low dopamine, like the shaky hands, anxiety, and depression. These are inhibitory receptors where serotonin inhibits the release of dopamine. This mat be hard getting used to. Hi all, Since my social anxiety is alleviated by low dose amisulpride which is supposed to raise dopamine level by inhibiting the D2 autoreceptors. That's the whole point of it. From novel/alternative substances, to established medications. So regardless of the levels, it has an effect on the brain. E. In addition, Carnosine also inhibits the enzyme that converts dopamine into norepinephrine. my panic attacks started after a week and a half of taking wellbutrin, which increases dopamine production (as i understand it). . The more this happens the more fatigued the dopamine receptors get. Interesting, I've never heard of using dry parsley. TFW you get anxiety about being late and missing the bus/plane/boat/show, sending you straight to the toilet, making you more late, which makes you more anxious, and around and around you go. It should increase dopamine more robustly than high dose Effexor (which, is still quite weak on dopamine). The substantia negra region of the brain has the densest population of dopamine synapses, and deterioration of this area is associated with Parkinson's disease. Due to all the excitatory stuff going on, our body downregulates cortisol to conserve energy and uses it only when we feel threatened. Triggered by perceived or actual scrutiny from others. While we can’t say “sauna treats anxiety” yet, we have enough evidence to suspect that it does. Causing brain fog, irritability, & fatigue. Have you lost anyone close to you recently? My health anxiety, and feeling totally convinced that I had some kind of cancer and was going to die, was linked to the fact that my dad had passed away from a sudden and aggressive cancer several months earlier. Look into Sensoril or Shoden patented Ashwagandha. This sub is for offering support, sharing experiences, sharing information, helping people in withdrawal or tapering. She talks about addiction to pleasure as well as to pain, an advocates for moderate use of both to maintain homeostasis. I was so anxious about taking Prozac because they say it can make you more anxious before it helps the anxiety. I was just reading about it the other day so I have no experience with it. true. I also had all these goals of going to the gym and eating healthy, but as the years went by, I was never able to build up a consistent habit and my anxiety continued to get worse. No it does not help with adhd or dopamine. Alright well you're free to think what you want but not only have dopaminergics and testosterone replacement been shown to improve social anxiety in healthy people, but in animal models testosterone boosts social dominance (with an inverse relationship to cortisol) and dopamine promotes social motivation and optimism. Taurine and tyrosine can help too. A common amino acid, glycine, can deliver a “slow-down” signal to the brain, likely contributing to major depression, anxiety and other mood disorders in some people, scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have found. It repeats that, in slightly different words. In addition to tackling addiction, many comments from my previous post were insightful. But there is the question of ethics as well. If you have anxiety it’s possible that a SDRI like Wellbutrin will cause you some more anxiety, whereas SSRI will treat both anxiety and depression. And my libido is higher than ever. This is a gradient, and it's how e. Only seretonin. For the anxiety part you should definitely try ashwagandha. All this excess stimulation stresses your brain, which in turn produces adrenaline and cortisol. Adhd is quite different hence why it is treated with stimulants. I tried bromantane and I find that it really helps my cognition/attention span/focusing/anxiety. In general anti-psychotic medications affect dopamine secretion in certain synapses, or dopamine re-uptake, or dopamine receptors, but this doesn't really tell us much. " Inositol increases serotonin and dopamine receptor densities. Reuptake inhibitors are nonselective and increase serotonin traffic at every receptor. The potential balance between flight or fight (and fright) is being extended far into the fight/fright region, with no option to achieve a flight stituation. But it makes also your low moments in life less depressive. I am currently taking concerta XL and it does have a great effect on anxiety levels, particular with stuff like mood swings. But you lower your dopamine release and you get used to that. I don't know if any one has experienced this kind of pain and anxiety during detox. Supporting those that are taking antidepressants for anxiety, depression, OCD, panic disorder, etc. Buspar contains those components which help to cure symptoms of anxiety such as fear, all kinds of stress, irritation, dizziness, rapid pulse and heartbeat and other physical symptoms connecting with anxiety. norepinephrine and oxytocin play some big rolls as we in romance. That along with too much cortisol. Stop doing those first and your dopamine will come back and cortisol will lower. It donates its methyl groups to comt. I also have something of a come-down after huge dopamine moments like danger or excitement or sexuality. g. As I said, about a month, but I took a lot. Your brain is still producing dopamine whether you're working or slacking off. Deficiencies in serotonin can result in depression. You need to take enough to reach equilibrium. While Lexapro is highly effective for anxiety and depression for many, an often mentioned side effect is tiredness, drowsiness, or fatigue with long-term use. Feeling as if the DLPA is lowering my dopamine instead of increasing it. But the reality is that nearly every hormone and every neurotransmitter can potentially cause anxiety, simply because anxiety is often a warning sign Not sure if dopamine is they “key”, but it might be part of the picture. For example, "You can observe business opportunities in dopamine too. Drugs like ecstasy or molly blow all your dopamine levels and take many days to replenish. Start with a Dopamine Detox, then maintain a Dopamine Fast. Aug 24, 2022 · There is evidence suggesting that improving dopamine levels could reduce social anxiety, and possibly other anxiety disorders. This is just a basic introduction to the biochemistry of anxiety. I already take 1000mcg of methylcobalamin with some methylfolate mixed in. SDRI is commonly known to increase anxiety in some people and is best used for depression only, or added later to an SSRI. I have set up a number of app blockers and parental controls on my devices to force me to do a dopamine detox. I started at 5mg buspirone as I tapered off Wellbutrin. After a few more days not only did the anxiety not improve much, but I also started to feel worse overall, culminating in yesterday, when I had pretty much a depressive/anhedonic episode. Went from 5>7. As too much norepinephrine might cause irritability and anxiety, this could be another mechanism involved in the anxiolytic effects of β-Alanine. Watch his video on dopamine and the analogy of the tidal wave pool. Magnesium Glycinate - 400-600mg / day split over day. I've always struggled with some anxiety (mostly social), attention deficit issues and mild (seasonal/situational) depression, as well as a proclivity to addiction and substance abuse that tends to arise with the others (primarily alcohol, and misusing my Vyvanse prescription). i stopped taking it shortly after because it was unbearable panic attacks every day, but then i started taking d3 supplements because i thought that my anxiety was just because of a I’ve never had anxiety in my life and it was always a good time using but one night anxiety just hit me while using and I’ve kept trying to control it but that was impossible for me I can’t touch it anymore because every single time I do anxiety kicks my ass hard and it’s so bad that my anxiety will last for hours off of just one line. That's how we evolved. Yes, you are absolutely correct, Vitamin B2 is needed for the monoamine oxidase enzyme, which functions in the metabolism of neurotransmitters, such as dopamine, serotonin, and norepinephrin, for normal functioning of the nervous system. Sabroxy also acts on the GABA-A (I think) receptor. So um it's the total protein to tryptophan ratio that determines tryptophan uptake into the brain. As I was cleaning out the cupboard of curiosities this evening, I found a bottle of L-Lysine and did a quick Google blitz -- the first article I landed on happened to deal with L-Lysine and While there are no large observational studies, there is plenty of research elucidating the mechanisms through which sauna mediates neurochemical signaling through things like norepinephrine and dopamine. This is a support group to help with impulsive behaviour towards Eating, Gaming, Gambling, Thrill, and Tech. Basically you never rest your mind. You are rewarding yourself when you deserve to get rewarded (socializing, working on your passions, being prodoctive (even after cleaning your room or making the bed can release dopamine if you make it a task you need to complete) It is also possible that this create a vicious cycle where your initial dopamine shortage push you to indulge in high dopamine activities and then your body downregulate dopamine senstivity pushing you to seek even more dopamine. Too little actual can resulr in addictive behaviors and depression. I stopped drinking almost two years ago. gg/r-anxiety | Please look over the rules before posting to the subreddit Nervousness isn’t anxiety, there are far more people with “anxiety” than those with actual anxiety disorders, for those where the feeling of nervousness and fasts hr etc. I feel like I have no purpose in life and the low-dopamine activities doesn't give me enough strength to wake up. Vitamin D administration results in the increased expression of COMT in VDR-expressing SH-SY5Y cells". I take Valium for this, but want to start tapering. If not, it is a natural/sustainable way to boost dopamine and serotonin Health anxiety is sometimes triggered by a death in the family. I used to be very active on social media but now I have deleted every app except Reddit (although I lately find myself getting addicted to Reddit too lol). And you can’t go wrong with maca, worst case is that you don’t get any effects. Dietary carbo-hydrates produce major, insulin-mediated decreases in thebranched-chain amino acids but lesser reductions in plasma tryp-tophan, thus raising the plasma tryptophan ratio (6, 9, 10) andfacilitating tryptophan’s entry into the brain (13). Sadly you said that it makes you more worked up. I hate that feeling. Carnosine reduces anxiety by multiple mechanisms, increased BDNF being a major one. Since these imbalances are what caused the depression or anxiety, depression would not affect the levels of serotonin and dopamine. Buspar (Buspirone) - is a special anti-anxiety medication, which has an influence upon your brain, where the feeling of anxiety arouses. i’ve never had one before that. In normal people this causes overwhelming anxiety. Even so far as trading peace for conflict while identifying as rational. Hello brother, i would suggest you read the book Dopamine nation or watch andrew huberman podcast with anna liembke, this is quite common, there's sort of a bell curve where your cravings will worsen but then they'll plateau and lower out, this 17-21 should be the last of it, usually after 3 to 4 weeks, your body behaves normally and sometimes it takes longer but after 4 weeks you'll be where Blockade of Dopamine D3 receptors raises GABA in Amygdala. Yes - my anxiety got worse at first but I think that was my own doing rather than the tablets necessarily. What do you guys think? Also, I have an appointment on the 7th, I'll of course talk to my doc/NP about it then. Another route to help speed up comt would be magnesium and HydroxoB12. ADHD meds work. Physical symptoms may include: blushing, excess sweating, trembling, palpitations, and nausea, stammering, along, rapid speech, panic attacks. And surprise surprise, Methylfolate is used during the making of serotonin and dopamine, the feel good/reward hormones. You’d have to wean off the Effexor and have a washout period before starting Nardil/phenelzine. Are low levels of dopamine and norepinephrine associated with anxiety too? You just get addicted to things like check your phone, post some stories, watch a lot of reels that make you sad because your life sucks and it makes your brain stimulated. I for example drink around a liter of green tea daily and feel as good as never before. Making your high moments in life like getting a promotion less enjoyable, because less dopamine is fired out. That's serotonin receptor density, and dopamine receptor density. There have also been many studies stating that meditation and yoga can help manage stress and anxiety, as well. Other treatment modalities are welcome as long as there is a clear intention towards symptom improvement, and at least a modest attempt at being scientific. Right. Deficiencies in dopamine can result in lack of motivation. That's not serotonin increase. The Dopamine-Anxiety Connection: Unraveling the Mystery. Sure, coffee is bad for anxiety given the high caffeine levels and the associated stimulation of the central nervous system. From reading people's experiences if they stick to a low amount and then back away because they encounter anxiety, they just get anxiety all over again the next time they try it. I'm currently diagnoses with generalized anxiety disorder, depression, and a panic disorder. Basically, Vitamin D speeds up the breakdown of Dopamine and Norepinephrine which increases the chances of ADHD or depression symptoms due to reduced dopamine & norepinephrine levels. Amongst the antipsychotics who aren't partial dopamine agonists I think olanzapine would be the best by far in unipolar depression(but also for anxiety and OCD) together with amisulpride; olanzapone preferentially binds to and blocks 5HT2 receptors in low dosages and might to help further disinhibit dopamine release by possibly preferentially Too much dopamine equals addictive behaviors and anxiety. 3) Caffeine generates dopamine, clonazepam keeps the caffeine from ALSO causing me panic/anxiety. My anxiety, although not completely fine, is considerably better with only a few flare ups a month. Jan 9, 2025 · At the same time, things that would normally give you some dopamine give you almost none when your dopamine receptors are downregulated. It is an antipsychotic, but at low doses it doesn't have a noticeable effect on dopamine. Dopamine is a chemical to be nourished, like you said it increases your motivation! A great natural supplement that boosts Dopamine is L tyrosine, the recommended dosage is one 800mg capsule a day. Not just dopamine, but they help me unwind after a difficult day. It's like a dieter losing the same five pounds. r/depressionregimens is a community focused on the research and discussion of treatments for depression and anxiety. leads to a longer lasting pain in the form of depression, anxiety, so on so forth. In fact, many types of depression are cause by an excess of serotonin and dopamine uptake. Now with 20 my anxiety has still been breaking through especially about 9-10 hrs after taking buspirone. The three of them are referred to as the love hormones. I have returned to Muay thai after a few years, and have begun BJJ(Gi), and these help me so much. You can supplement all the l tyrosine you want, but without additional tyrosine hydroxylase you won't be getting any additional dopamine. And also fasting 78 votes, 133 comments. Perhaps something more interesting to look at is dopamine fasting. I know prolactin and dopamine have an interesting reaction I don't quite fully understand but have been trying to research. Depression and anxiety are due to pathologically under-active neurons, so medicines that promote or increase activity will stimulate growth and regeneration of those neurons given time. Or check it out in the app stores TOPICS Reduce Anxiety via Dopamine D3 Receptors L-Lysine is a substance that I'd read a good deal about at some point in the past, though more from a general nutrition and fitness-oriented standpoint. Eventually, I listened to Huberman’s podcast about regulating dopamine and a lightbulb went off in my head. My overall happiness is through the roof. So any dopamine produced In the body is stuck there - having no effect on your mood but increasing blood pressure. Because bromantane enhances dopamine synthesis, would I benefit from other nootropics like Ritalin/Adderall/Selegine that are dopamine modulators?? Anybody have any similar experiences? 272 votes, 86 comments. So by increasing it there, you might see a decrease in dopamine activity. Oddly enough, I have fibromyalgia, have a history of chronic stress dating back 15 years (familial abuse), and have IBS which up until recently wasn't letting me process over half of the food I ate. It’s approaching the end of week four and I’m noticing my ADHD symptoms have become more pronounced. Slow COMT is associated with high tonic dopamine. And you'll start to feel like crap, with anxiety and all kinds of issues increasing. 5mg would count as micro dosing. Welcome to Dopamine Detoxing. When you start to control your dopamine you start to live a simpler life and then your anxiety tends to go away. The reason could be interaction between serotonin and dopamine in the brain. I (27f) deal with ADHD, anxiety, and depression - all unmedicated. People with the mutation have reduced ability to make this conversion so have lower levels of Methylfolate. NAC averages out how you feel in life in different situations. I have anxiety disorder and I wake up with anxiety a lot of mornings. To give some context, I had already was on a week-long sugar fast due to overdoing it on sugar looking for that high (from finals) and getting a bladder infection. Technically you could try to estimate the total amount in the brain but it would be meaningless, because the "level" of dopamine that neuron A is releasing could be totally different from the level of dopamine that neuron X is releasing, and they might mean opposite things: when A releases dopamine it means "initiate arm movement now," but when And so you'll have to seek out greater and greater thrills to get the same rush. So if you want to deal with that and avoid this outcome, then you need to actively avoid most instant gratitification and get used to low amounts of dopamine. It may not be the best medication if you're already lacking motivation, but it will definitely help tame your anxiety and lift your mood. I doubt that caffeine has a significant impact on serotonin levels. Inositol helps boost serotonin and dopamine receptor density. ) Anyway. Nicotine is a stimulant and also increases Dopamine, however (1) increased Dopamine does not cause increased anxiety, and (2) the act of indulging an addiction and relieving or satisfying a craving for something you're addicted to (Nicotine in this case), relieves anxiety temporarily even if the substance itself does not. Nardil/phenelzine has a good reputation for social anxiety. This makes the pulses of dopamine small in comparison. I am still struggling with too much binge watching. I think my dopamine addiction had something to do with my high levels of anxiety, but it was never really clear until I went on a 24-hour detox. Does Zoloft/sertraline decrease dopamine levels? As well as an autism spectrum disorder, I have a severe case of ADD and I’m worried Zoloft is depleting my dopamine levels further. The obvious one is dopamine but I've heard that the drug also raises norepinephrine too. Very good for reducing stress. Would it be a good idea to try some dopamine agonists like Mirapex or Requip for my social anxiety? Vitamin B6 P5P form - Required for both serotonin and dopamine Zinc Picolinate - but be careful - you can take too much. When I think about anxiety/depression, serotonin is always the neurotransmitter that comes to mind (low levels exacerbate them). Notice that it doesn't say "increases serotonin. beywa uka tvzflju zyebdnj eko xeja tod mcakls acomoo jqvbuib agjegim fsdzqi jbxfnvk iflu ijtbvc